The multi-screen booking engine architected around HTML and the traditional web development model has largely been the norm since the advent of transactional technologies on the Internet. However, with the rapid advancement of web based technologies such as Rich Internet Applications, users can now peruse and compare information using intuitive interfaces that are relatively richer in interactivity and responsiveness. This has resulted in the emergence of booking interfaces that enable the booking process to be completed within a single-screen or frame. The purpose of this study was to examine usability differences between the single-screen and multi-screen booking interface within a hotel reservation context. Two intermediary websites (one single-screen and the other multi-screen) were taken and evaluated for usability differences. Findings show no differences over operational parameters of usability between the two websites. However, specific to contextual parameters of usability, the single-screen interface reported significantly greater evaluations when it came to efficiency, memorability and error recovery. Lastly, the established multi-screen booking website reported greater satisfaction evaluations over its single-screen counterpart. Findings of the study can be used to improve the quality of interfaces and enhance the research agenda.